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Plexin-B1 mutations in prostate cancer.
Wong OG, Nitkunan T, Oinuma I, Zhou C, Blanc V, Brown RS, Bott SR, Nariculam J, Box G, Munson P, Constantinou J, Feneley MR, Klocker H, Eccles SA, Negishi M, Freeman A, Masters JR, Williamson M. Wong OG, et al. Proc Natl Acad Sci U S A. 2007 Nov 27;104(48):19040-5. doi: 10.1073/pnas.0702544104. Epub 2007 Nov 16. Proc Natl Acad Sci U S A. 2007. PMID: 18024597 Free PMC article.
Mutations were found in 89% (8 of 9) of prostate cancer bone metastases, in 41% (7 of 17) of lymph node metastases, and in 46% (41 of 89) of primary cancers. ...Overexpression of the Plexin-B1 protein was found in the majority of primary tumors. The mutations hinder …
Mutations were found in 89% (8 of 9) of prostate cancer bone metastases, in 41% (7 of 17) of lymph node metastases, and in 46% …
RASAL2 promotes tumor progression through LATS2/YAP1 axis of hippo signaling pathway in colorectal cancer.
Pan Y, Tong JHM, Lung RWM, Kang W, Kwan JSH, Chak WP, Tin KY, Chung LY, Wu F, Ng SSM, Mak TWC, Yu J, Lo KW, Chan AWH, To KF. Pan Y, et al. Mol Cancer. 2018 Jul 23;17(1):102. doi: 10.1186/s12943-018-0853-6. Mol Cancer. 2018. PMID: 30037330 Free PMC article.
RASAL2 encodes a RAS-GTPase-activating protein (RAS-GAP) and showed increased expression in CRC cell lines and clinical specimens. Higher RASAL2 expression was significantly correlated with lymph node involvement and distant metastasis in CRC patients. Moreover, we …
RASAL2 encodes a RAS-GTPase-activating protein (RAS-GAP) and showed increased expression in CRC cell lines and clinical specimens. Higher RA …
FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation.
Nelms K, Snow AL, Hu-Li J, Paul WE. Nelms K, et al. Immunity. 1998 Jul;9(1):13-24. doi: 10.1016/s1074-7613(00)80584-1. Immunity. 1998. PMID: 9697832 Free article.
Here, we describe a PTB domain protein, FRIP, that is phosphorylated in response to cytokine stimulation. FRIP is related to the rasGAP-associated protein p62dok and is bound by the N-terminal SH2 domain of rasGAP. The frip gene maps to the hairless (hr) locus on mo …
Here, we describe a PTB domain protein, FRIP, that is phosphorylated in response to cytokine stimulation. FRIP is related to the rasGAP …
[Dectection of G3BP and CD44v6 in the tissues of laryngeal squamous cell carcinoma and their clinical significance].
Luo D, Lou W. Luo D, et al. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2017 Jul;33(7):977-982. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2017. PMID: 28712408 Chinese.
The positive rates of G3BP and CD44v6 in cancer tissues were related with the clinical stage, recurrence or metastasis, and lymph node metastasis of laryngeal squamous cell carcinoma, but had nothing to do with patients' age and tumor size. ...
The positive rates of G3BP and CD44v6 in cancer tissues were related with the clinical stage, recurrence or metastasis, and lymph …
[Monoclonal antibody against G3BP: preparation, characterization and its application in analysis of human tumors].
Ning JY, You JF, Pei F, Wang JL, Cui XL, Zheng J. Ning JY, et al. Zhonghua Bing Li Xue Za Zhi. 2005 Apr;34(4):215-9. Zhonghua Bing Li Xue Za Zhi. 2005. PMID: 16091175 Chinese.
In breast cancer specimens, the degree of G3BP expression correlated positively with the presence of lymph node metastasis and c-erbB2 expression. CONCLUSIONS: The G3BP-specific monoclonal antibody derived from recombination protein can be used in ELISA, Western blo …
In breast cancer specimens, the degree of G3BP expression correlated positively with the presence of lymph node metastasis and …